Anti-TIMP1 Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human

產(chǎn)品型號：K101524P

更新時間：2022-08-15

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Anti-TIMP1 Polyclonal Antibody

英文名稱	Anti-TIMP1 Polyclonal Antibody
宿主	Rabbit
別名	ABH;ABH1;ALKBH;alkB;hABH
應用	WB
稀釋比例	WB 1:3000.
交叉反應	Human
蛋白分子量	33kDa
Gene ID	7076
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human TIMP1
性狀	液體
Public Immunogen Range	A synthetic peptide of human TIMP1
Subcellular Locations	Secreted
Swiss Prot	P01033
克隆類型	Polyclonal Antibody
背景資料	Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.