Anti-ITA2B Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human

產(chǎn)品型號：fk2985Y

更新時間：2022-08-15

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Anti-ITA2B Polyclonal Antibody

英文名稱	Anti-ITA2B Polyclonal Antibody
宿主	Rabbit
別名	ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
應用	WB
稀釋比例	WB 1:3000.
交叉反應	Human
蛋白分子量	113kDa
Gene ID	3174
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human ITA2B
性狀	液體
Public Immunogen Range	A synthetic peptide of human ITA2B
Subcellular Locations	Cytoplasm Cell membrane
Swiss Prot	P08514
克隆類型	Polyclonal Antibody
背景資料	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.