Anti-MYC Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應Human Mouse Rat

產品型號：K106458P

更新時間：2022-08-15

廠商性質：生產廠家

訪問量：1242

服務熱線

010-50973130

立即咨詢

產品分類

PRODUCT CLASSIFICATION

產品介紹

Anti-MYC Polyclonal Antibody

英文名稱	Anti-MYC Polyclonal Antibody
宿主	Rabbit
別名	BHLHE39;c-Myc;MRTL;MYCC
應用	WB IHC
稀釋比例	WB 1:2000-5000.IHC 1:50-200.
交叉反應	Human Mouse Rat
蛋白分子量	63kDa
Gene ID	4609
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human MYC
性狀	液體
Public Immunogen Range	A synthetic peptide of human MYC
Swiss Prot	P01106
Subcellular Locations	Nucleus Cytoplasm
克隆類型	Polyclonal Antibody
背景資料	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.