Anti-SOCS1 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應Human Mouse Rat

產(chǎn)品型號：K106494P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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Anti-SOCS1 Polyclonal Antibody

英文名稱	Anti-SOCS1 Polyclonal Antibody
宿主	Rabbit
別名	CIS1;CISH1;JAB;SOCS-1;SSI-1;SSI1;TIP-3;TIP3
應用	WB IHC
稀釋比例	WB 1:2000-5000.IHC 1:50-200.
交叉反應	Human Mouse Rat
蛋白分子量	33kDa
Gene ID	8651
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human SOCS1
性狀	液體
Public Immunogen Range	A synthetic peptide of human SOCS1
Subcellular Locations	Cytoplasm
Swiss Prot	O15524
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.