Anti-NQO1 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106519P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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Anti-NQO1 Polyclonal Antibody

英文名稱	Anti-NQO1 Polyclonal Antibody
宿主	Rabbit
別名	DHQU;DIA4;DTD;NMOR1;NMORI;QR1
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	27kDa
Gene ID	1728
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human NQO1
性狀	液體
Public Immunogen Range	A synthetic peptide of human NQO1
Subcellular Locations	Cytoplasm Cell membrane
Swiss Prot	P15559
克隆類型	Polyclonal Antibody
背景資料	This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.