Anti-KRT18 Polyclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號(hào)：K106590P

更新時(shí)間：2022-08-15

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Anti-KRT18 Polyclonal Antibody

英文名稱(chēng)	Anti-KRT18 Polyclonal Antibody
宿主	Rabbit
別名	CK-18;CYK18;K18;PIG46;Cytokeratin-18
應(yīng)用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:50-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	26kDa
Gene ID	3875
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human KRT18
性狀	液體
Public Immunogen Range	Recombinant protein of human KRT18
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P05783
克隆類(lèi)型	Polyclonal Antibody
背景資料	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.