Anti-TERT Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng)Mouse

產(chǎn)品型號：K106629P

更新時(shí)間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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Anti-TERT Polyclonal Antibody

英文名稱	Anti-TERT Polyclonal Antibody
宿主	Rabbit
別名	EST2;TCS1;TRT;HEST2;TP2
應(yīng)用	IHC
稀釋比例	IHC 1:50-200.
交叉反應(yīng)	Mouse
蛋白分子量	127kDa
Gene ID	7015
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human TERT
性狀	液體
Public Immunogen Range	A synthetic peptide of human TERT
Subcellular Locations	Cytoplasm
Swiss Prot	O14746
克隆類型	Polyclonal Antibody
背景資料	Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats.