Anti-AKR1C3 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human

產(chǎn)品型號：K106744P

更新時間：2022-08-14

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Anti-AKR1C3 Polyclonal Antibody

英文名稱	Anti-AKR1C3 Polyclonal Antibody
宿主	Rabbit
別名	DDX;HAKRB;HSD17B5;KIAA0119;PGFS
應(yīng)用	WB
稀釋比例	WB 1:500-2000.
交叉反應(yīng)	Human
蛋白分子量	37kDa
Gene ID	8644
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human AKR1C3
性狀	液體
Public Immunogen Range	Recombinant protein of human AKR1C3
Subcellular Locations	Cytoplasm
Swiss Prot	P42330
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.