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當(dāng)前位置:首頁(yè)產(chǎn)品中心細(xì)胞相關(guān)產(chǎn)品細(xì)胞因子P00025Recombinant Human IL-15細(xì)胞因子

Recombinant Human IL-15細(xì)胞因子
產(chǎn)品簡(jiǎn)介:

Recombinant Human Interleukin-15(Recombinant Human IL-15細(xì)胞因子) is produced by our E.coli expression system and the target gene encoding<br>Asn49-Ser162 is expressed.

產(chǎn)品型號(hào):P00025

更新時(shí)間:2025-08-29

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產(chǎn)品介紹

Recombinant Human IL-15細(xì)胞因子 

Known asInterleukin-15; IL-15; IL15
Derived fromE.coli
PurityMeasured by the dose dependent stimulation of mouse CTLL-2 cell proliferation.ED50 is less than 0.5 ng/ml. Specific Activity of 2.0 x 10^6 IU/mg.Greater than 95% as determined by reducing SDS-PAGE.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 9 months
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 7X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
EndotoxinLess than 0.1 ng/ug (1 IEU/ug).
Amino Acid SequenceNWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKE CEELEEKNIKEFLQSFVHIVQMFINTS
BackgroundHuman Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.

Recombinant Human Interleukin-15 is produced by our E.coli expression system and the target gene encoding Asn49-Ser162 is expressed.

 

Recombinant Human IL-15細(xì)胞因子訂購(gòu)說(shuō)明:

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4、每日訂單截止時(shí)間為16點(diǎn)整,部分城市可到17點(diǎn)整,因超過(guò)截止時(shí)間造成當(dāng)日不能發(fā)貨的將于次日安排發(fā)貨。
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